Areas of Practice
Saturation Genome Editing (SGE) is a CRISPR/Cas9-based method to functionally test the effects of large numbers of variants in their native genomic context.
The Single Cell Genomics Group of the Brotman Baty Institute’s Advanced Technology Lab (BAT-Lab) specializes in high-throughput single-cell genomics, offering cutting-edge single-nucleus RNA-sequencing (snRNA-seq) and ATAC-sequencing (snATAC-seq). Using combinatorial indexing, our team delivers cost-effective, scalable solutions that profile hundreds of thousands to millions of nuclei in a single experiment. These efforts have supported large-scale research initiatives such as the Human BioMolecular Atlas Program, Human Cell Atlas, and the NIH BRAIN Initiative. We are also open to collaborating with investigators to explore and implement new technologies.
The Starita Lab is currently accepting graduate students and postdocs.
This team started as a 2018 as a research-only surveillance platform for respiratory pathogen detection and influenza sequencing, but quickly shifted into clinical-grade testing as the COVID-19 pandemic erupted. For its six year run, the pathogen detection laboratory supported testing and sequencing efforts across major studies including the Seattle Flu Study/Alliance, Husky Coronavirus Testing, and the CASCADIA Study.